their own hypersensibilities and emotional history, develop a number of
chronic symptoms. Patients treated with cannabinoids report the
improvement of the following list of symptoms. Few scientific works
have adressed scientificaly this field of research
doctors have been able to evaluate efficiency and validate cannabinoids
use in a large number of ADHD cases. Dr
Bearman, practicing in Santa Barbara Area, has write some
specific articles on it.
For each symptom presented in the following list, a brief
scientific explanation is given to show the implication of
Hyper-impulsivity (restless, agitation,
adrenaline stress, restless legs syndrome) : THC,
main psycho-active phyto-cannabinoïd constituent of cannabis,
is an agonist of
endocannabinoid amandamine. It is binding to the CB1 receptors present
number in the brain. It stimulates the retrograde signalling inhibition
neuronal synapses. Consequences are modulation and decrease of neuronal
activity, thus having a powerful calming effect associated. This
on mice in 2003.
including intestinal pains due to stressful situations
his proven to be anxiolytic at low doses, but anxiogenic at higher
depending on individual tolerance. Another phyto-cannabinoïd
psychoactive cannabidiol, acts complementary to THC. CBD binds to a
category of cannabinoid receptors, CB2, which are known to be
implicated in the
neuro-immune system modulation. CBD is mainly present in hemp and
hashish, in various quantity. It
is largely known as an anti-anxiety agent. It also has the advantage to
reduce THC psychoactive and adverse effects. ADHD patients report a
effect on intestinal pains and general anxiety state when CBD
added to THC.
- Fears /
Panic attacks : CB1
receptors are implicated in synaptic plasticity and emotional responses
external stimuli. It is proven on mice that THC helps in the process of
deficient mice exhibits abnormal impulsive and fearful
behaviour and continue to be over-stressed comparing to normal mice.
- Hypersensibility to stressful
situations, emotions, ... : same
of THC/CBD as on anxiety and fear.
- Lack of
attention : THC
the ADHD brain over-activity, helping the patient to stay focused and
attentive. A clinical
case report in Germany
(2008) exposes the result
of an ADHD driver attention performances test under cannabis.
- Insomnia : THC
the brain and helps quality of sleep.
- Depressive tendency : THC
to CB1 receptorswhich
have also been
identified to be involved in the release of serotonine in pre-synaptic
Serotonine is the natural brain anti-depressant agent (case
study, Dr Blass, Austria).
- Suicidal Tendency / Death ideation
- Alcoholism Tendency : all
patients who have been alcoholic report the efficiency of cannabis as a
- Drugs Abuse Tendency (cocaine,
heroine, ...) : same